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Nanomedicine transdermal delivery preparation is a novel preparation that uses nanotechnology to wrap or couple drugs to nanoscale carriers to deliver drugs to the body by skin surface or microneedle puncture. Nanomedicine transcutaneous delivery agents are highly biocompatible, tunable and functional and can be used to treat a variety of diseases, such as cancer, inflammation, infection, skin diseases, etc. Transcutaneous delivery of nanodrugs can improve the targeting and bioavailability of drugs, reduce toxic and side effects, and enhance therapeutic effects.

The application of nanoparticle-based percutaneous drug delivery system in the treatment of skin diseases, including metal nanoparticles, polymer nanoparticles, liposomes, solid lipid nanoparticles, etc. The preparation methods, characteristics and advantages of different types of nanoparticles and demonstrate their application and prospects in the treatment of many types of skin diseases.