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Long wavelength light response to medical materials and technology is a new technology that uses long wavelength light (such as near infrared light) to activate or regulate the performance and function of medical materials. With strong tissue penetration and low biological absorption, long-wavelength light can achieve non-invasive or minimally invasive intervention and treatment for deep tissues. Long-wavelength light-responsive medical materials include various types of organic, inorganic and hybrid materials, which can be designed and synthesized according to different application requirements to realize the targeted delivery, release, regulation and imaging of drugs, genes, cells, etc. Long-wave length optical response medical materials and technology have the advantages of high efficiency, precision and multifunctional, and it is a new medical technology with broad prospects.