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Hydrogels:3D printing bracket

Hydrogels:3D printing bracket

【Numbering】BK2020121708 【CAS】
【Item No.】BK2020121708-03 【specification】
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Due to its soft and brittle properties, high-precision mass production of hydrogels has always been a problem in the industry, and medical applications such as mass tissue regeneration require repeatable batch hydrogel structures. Projection-type light-curing 3D printing is a feasible method to solve high-precision mass production of hydrogels. However, due to the biocompatibility requirements of hydrogels, DLP printers that stably achieve soft and brittle bio-hydrogel printing have been stuck in In the laboratory stage, no mature equipment was introduced. The team has been researching for several years, optimized a large number of forming processes and core designs, solved the stability problem in printing, and launched the world's first commercialized projection-type light-curing biological 3D printer (BKNM-BP8600), which is especially suitable for medical applications A large number of consistent scaffold samples are required. In order to meet the needs of researchers who do not have BP8600, a customized service for hydrogel biological scaffolds is launched.

The accuracy of conventional 3D printing polymers can only be controlled in the order of 100-200 microns (mainly refers to the diameter of the printed fiber). Considering that the size of the cell is about 10 microns, if you print a biological scaffold, a column with a thickness of 100 microns is 10 Micron-sized cells are a bit like a mountain, and the efficiency of cells crawling across the scaffold is very low. If the wire diameter of the scaffold is reduced to be close to or even smaller than the cell size, what interesting phenomena will there be?

The team has many years of accumulation in the manufacture of ultra-high-precision scaffolds. The wire diameter of the scaffold can be controlled from 3-50 microns, and the pure structure can be realized on the high-precision scaffold to regulate cell growth. For example, we found that cells can grow like bamboo... …In addition to regenerative medicine applications, high-precision scaffolds have the advantages of large specific surface area, good flexibility, and high porosity due to the micro-nano fibers contained in them. They can also be widely used in biochemical sensing and other fields. Related research has been published in Materials Horizons, Small, Biofabrication and other well-known journals (click to view the special introduction), and the stent customization service is now available.


Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance

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